From the East side:
Take I-70 West
Take exit #101A/Cleveland/Broad St on I-71N
Take exit #109BAirport onto Hamilton Avenue toward Leonard Avenue
Turn Right onto Old Leonard Avenue
Turn Right onto St. Clair Avenue
Arrive at 461 St. Clair Avenue on your right

From the West side:
Take I-70 East
Take exit #101A/Cleveland onto I-71N
Take exit #109BAirport onto Hamilton Avenue toward Leonard Avenue
Turn Right onto Old Leonard Avenue
Turn Right onto St. Clair Avenue
Arrive at 461 St. Clair Avenue on your right

From the North side:
Take I-270 S toward Wheeling
Take exit #35A/Airport onto I-670 W
Take exit #5/I-71 towards Cincinncati/Leonard Ave./Cleveland Avenue
Turn Right on Jack Gibbs Blvd.
Continue on Leonard Avenue
Make sharp Right on St. Clair Avenue
Arrive at 461 St. Clair Avenue on your right

From the South side:
Take I-71N toward Columbus
Take the Cleveland/Wheeling exit  onto I-70E
Take exit #101A/Cleveland onto I-71N
Take exit #109B Airport  onto Hamilton Avenue towards Leonard Avenue
Turn Right onto Old Leonard Avenue
Turn Right onto St. Clair Avenue
Arrive at 461 St. Clair Avenue on your right